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Abametapir

Class
Pediculicides
Subclass
Metalloproteinase inhibitors
Generic name
Abametapir
Brand names
Xeglyze®
Common formulations
Lotion
Dosage and administration
Adults patients
Treatment of head lice
•
0.74% TOP once
Indications for use
Labeled indications
Adults
•
Treatment of head lice
Children
•
Treatment of head lice
Specific populations
Renal impairment
eGFR 0-90 mL/min/1.73 m²
•
Use acceptable. No dose adjustment required.
Renal replacement therapy
Any modality
•
Use acceptable. No dose adjustment required.
Hepatic impairment
Any severity
•
No guidance available.
Pregnancy and breastfeeding
Pregnancy
All trimesters • Australia Category: C
•
Use only if benefits outweigh potential risks. Evidence of fetal harm in animals.
Adverse reactions
Common 1-10%
•
Contact dermatitis, burning sensation, eye irritation, hair discoloration, skin rash, vomiting, skin erythema
Unknown frequency
•
Drug hypersensitivity reaction, scalp erythema
Interactions
Drug(s)
Check Interactions
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