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Digoxin toxicity

Guidelines

Key sources

The following summarized guidelines for the management of digoxin toxicity are prepared by our editorial team based on guidelines from the American Heart Association (AHA 2023), the American Heart Association (AHA/HRS/ACC 2019), and the Extracorporeal Treatments in Poisoning Workgroup (EXTRIP 2016).
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Medical management

Digoxin immune Fab: as per AHA 2023 guidelines, administer digoxin immune fAb in patients with digoxin or digitoxin poisoning.
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  • Management of arrhythmias

Therapeutic procedures

Temporary cardiac pacing: as per AHA 2023 guidelines, consider attempting electrical pacing for the management of bradyarrhythmias in patients with digoxin or other cardiac glycoside poisoning.
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  • ECTR

Specific circumstances

Patients with toad venom poisoning: as per AHA 2023 guidelines, consider administering digoxin immune fAb in patients with Bufo toad venom poisoning.
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