Revised International Prognostic Scoring System (IPSS-R) for myelodysplastic syndrome
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When to use
Cytogenetic group
Very good: -Y or del11q)
Good: normal karyotype, del5q), del12p), del20q) or double including del5q)
Intermediate: del7q), +8, +19, i17q) or any other single or double independent clone
Poor: -7, inv3)/t3q)/del3q), double including -7/del7q), or complex 3 abnormalities
Very poor: complex > 3 abnormalities
Medullary blasts, %
≤ 2
2-5
5-10
> 10
Hemoglobin, g/dL
≥ 10
8-10
< 8
Platelets, cells/mm**3
≥ 100,000
50,000-100,000
< 50,000
Absolute neutrophil count, cells/mm**3
≥ 800
< 800
Calculation
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