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Frequently Asked Questions

Who is Pathway for?  

Pathway is for licensed medical doctors, medical residents, medical students and other licensed healthcare professionals.  

What does Pathway do?  

Pathway is designed to give you quick and easy access to the highest quality and most recent evidence-based clinical information through a variety of digital reference tools, so you can optimize your decision-making, stay up-to-date and provide better care.

Which specialties does Pathway cover?

Pathway provides broad coverage of adult medicine across 33 specialties: Allergy and Immunology, Anesthesia, Cardiology, Cardiothoracic Surgery, Critical Care, Dermatology, Emergency Medicine, Endocrinology, Gastroenterology, General Surgery, Genetics, Geriatrics, Gynecology, Hematology, Hepatology, Infectious Diseases, Internal Medicine, Medical Biochemistry, Nephrology, Neurology, Neurosurgery, Nutrition, Obstetrics, Orthopedic, Surgery, Otolaryngology, Primary Care, Psychiatry, Respirology, Urology, Vascular Surgery

What are the criteria for guidelines to be included in Pathway’s database?  

In order to be included in Pathway's database, guidelines must:  

  • Be available online, in the English language, and published in a peer-reviewed journal.
  • Be produced by a recognized medical specialty association, a professional medical society, or a recognized group of medical experts.
  • Adhere to a transparent and evidence-based search methodology that provides a verifiable systematic review of the evidence.
  • Provide specific recommendations on patient care as well as an objective assessment of the supporting evidence and of the benefits and harms of the proposed tests and/or interventions.
  • Provide explicit disclosure of the guideline author's conflicts of interests.

All guidelines are manually reviewed by our team for quality and relevance prior to inclusion in the database.

What other data sources are included in the database?  

Pathway supplements clinical guideline recommendations with summarized results from high quality primary sources, including meta-analyses and randomized controlled trials.

What is Pathway's peer review process?  

Pathway places the utmost importance on providing high quality content. Peer review is in place at multiple steps in Pathway's editorial pipeline in order to ensure the accuracy and objectivity of our content. Summaries of recommendations as well as interactive algorithms are crafted by physician authors and peer reviewed.

How frequently is Pathway updated?  

Pathway is updated regularly following a comprehensive electronic search of peer-reviewed journals, clinical databases and other resources. All efforts are made to include summaries of new guidelines in our database within 3 months of their publication.  

How does Pathway assign evidence grades?  

The recommendation strengths and levels of evidence are always based on the original guideline publication. Pathway does not re-appraise primary evidence sources for recommendations.

In order to maintain consistency in the formulation of summarized recommendations, a distinction is established between “strong” and “conditional” recommendations. Strong recommendations are indicated by the use of the imperative tense, such as ‘Treat’ or ‘Offer,’ while conditional recommendations are indicated by the use of the verb ‘Consider.’  

The strength of a recommendation is interpreted to reflect the risk/benefit balance of a specific test or intervention, rather than being mechanically derived from evidence quality. In cases where recommendation strength is not formally given, or does not incorporate a risk/benefit assessment, the strength of the wording used in summarized recommendations aligns as closely as possible with the strength of wording found in the original recommendation.  

Color-coded indicators are provided as visual indicators of the level of evidence supporting a recommendation.  

What is Pathway's conflict of interest policy?  

Pathway employees operate under strict conflict of interest rules. Pathway Medical employees may not work or consult for, own stock in, or receive payment or gifts from the medical device, pharmaceutical, or biotechnology industry. See our Conflict of Interest Policy for further details.  

How do I submit new guidelines for inclusion?

We welcome new guideline submissions, provided that the guideline meets our inclusion criteria. Please send any inquiries or suggestions at